Drug Standards
Medchemexpress LLC Benzoic acid, 2-methoxy-5-methyl-, methyl ester | 63113-79-1 | MFCD06411343 | 1g
Ilurodoline impurity 10 is an impurity of Ilurodoline
Sigma Aldrich Fine Chemicals Biosciences Irbesartan | 138402-11-6 | MFCD00864464 | 10 mg
Irbesartan | Purity: ≥98% | Mol Wt: 428.53 | 138402-11-6 | MFCD00864464 | 10 mg
Apexbio Technology LLC Losartan Potassium (DuP 753) 124750-99-8 10mM (in 1mL DMSO)
Losartan Potassium (DuP 753 CAS 124750-99-8) is a small molecule antagonist selective toward angiotensin AT receptors By competitively blocking AT receptors it inhibits angiotensin II-mediated vasoconstriction demonstrated by antagonism of contractile responses in isolated rabbit aortic and jugular vein tissues (pA 8 27) As an orally bioavailable agent losartan potassium is frequently utilized in cardiovascular research notably in studies investigating hypertension and associated mechanisms of angiotensin II signaling
Selleck Chemical LLC Hypromellose S4444-1g
Hypromellose (Hydroxypropyl Methyl Cellulose HPMC Celacol HPM 5000) is a commonly employed cellulose ether used in the fabrication of hydrophilic matrices Hypromellose provides the release of a drug in a controlled manner effectively increasing the duration of release of a drug to prolong its therapeutic effect
Medchemexpress LLC Ibrutinib methoxy impurity | 2031255-26-0 | MFCD34184521 | 10mg
Ibrutinib Impurity 14 is an impurity of Ibrutinib (HY-10997)
Cayman Chemical RacecadotrIl 500mg
A prodrug form of thiorphan; reduces or prevents castor oil-induced diarrhea without delaying intestinal transit in rats at 80 or 100 mg/kg, respectively; decreases duration of diarrhea and increases body weight gain in a neonatal gnotobiotic pig model of human rotavirus-induced diarrhea
Apexbio Technology LLC Indapamide 26807-65-8 10mM (in 1mL DMSO)
Indapamide (CAS 26807-65-8) is a sulphonamide-derived diuretic structurally distinct from thiazides It functions by inhibiting sodium reabsorption primarily at the distal convoluted tubules of the nephron resulting in increased excretion of sodium and water This action reduces plasma volume and peripheral vascular resistance contributing to its antihypertensive effects Indapamide is also studied for its utility in models of decompensated cardiac failure due to its natriuretic and vasodilatory properties making it relevant for research into cardiovascular disease and fluid balance regulation
Medchemexpress LLC HKI-357 | 848133-17-5 | MFCD26792555 | 99.2% | 574.05 g/mol | C31H29ClFN5O3 | 100 MG
HKI-357 is a small-molecule, irreversible dual inhibitor of EGFR and ERBB2 with low-nanomolar potency. It inhibits EGFR (IC50 34 nM) and ERBB2 (IC50 33 nM), suppresses EGFR autophosphorylation at Y1068, and reduces AKT and MAPK phosphorylation. HKI-357 is used in biochemical assays and cell-based studies to probe EGFR/ERBB2 signaling and evaluate inhibitor activity in preclinical cancer research.
- Irreversible dual inhibitor of EGFR and ERBB2 with IC50s of 34 nM and 33 nM.
- Suppresses EGFR autophosphorylation (Y1068) and downstream AKT and MAPK phosphorylation.
- High purity (99.2% by HPLC) suitable for research applications.
- Available in milligram quantities for dose-ranging and assay setup.
- Suited for biochemical kinase assays and cell signaling studies.
Medchemexpress LLC 2-chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carbaldehyde | 2169267-53-0 | 50mg
Vonoprazan impurity 46 is an impurity of Vonoprazan (HY-100007)
Medchemexpress LLC 1-[(2-fluorophenyl)carbamoyl]cyclopropane-1-carboxylic acid | 918642-61-2 | MFCD16676129 | 25mg
Cabozantinib impurity 1 is an impurity of Cabozantinib (HY-13016)
Medchemexpress LLC Vonoprazan impurity 1 | 1807642-39-2 | 10mg
Vonoprazan impurity 1 is an impurity of Vonoprazan (HY-100007)
Sigma Aldrich Fine Chemicals Biosciences o-Iodohippuric acid United States Pharmacopeia (USP) Reference Standard | 147-58-0 | MFCD00002694 | 100MG
o-Iodohippuric acid United States Pharmacopeia (USP) Reference Standard | Mol Wt: 305.07 | 147-58-0 | MFCD00002694 | 100MG
Medchemexpress LLC Benazepril hydrochloride | 86541-74-4 | MFCD00895734 | 100.0% | C24H29ClN2O5 | 1 G
Benazepril hydrochloride is an orally active angiotensin-converting enzyme (ACE) inhibitor that reduces angiotensin-II production. It inhibits oxidative stress and apoptosis via the PI3K/Akt signaling pathway and improves diabetic nephropathy and decreases proteinuria. It is used in the study of hypertension, heart failure, and diabetic nephropathy.
- Orally active ACE inhibitor
- Reduces angiotensin-II production
- Inhibits oxidative stress and apoptosis
- Improves diabetic nephropathy
- Decreases proteinuria
- White to off-white solid appearance
- For research use only